Clinical characteristics and prognosis in systemic lupus erythematosus-associated pulmonary arterial hypertension based on consensus clustering and risk prediction model

Table 2 Comparison of RHC parameters between cluster 1 and cluster 2 in SLE-PAH patients at baseline assessment

RHC parameters	Overall (n = 46)	Cluster 1 (n = 38)	Cluster 2 (n = 8)	P-value*
mPAP (mmHg)	40.0 (28.8, 49.3)	39.5 (28.0, 49.3)	42.5 (34.0, 51.3)	0.270
PAWP (mmHg)	5.0 (4.0, 7.0)	5.5 (4.0, 7.0)	4 (3.0, 8.8)	0.518
PVR (WU)	6.5 (4.6, 9.9)	6.4 (4.1, 9.4)	10.1 (5.6, 13.4)	0.044
CI (L/min × m²)	3.3 (2.5, 3.7)	3.4 (2.8, 3.7)	2.3 (2.1, 2.8)	0.005
RAP (mmHg)	3.0 (2.0, 3.0)	3.0 (2.0, 5.0)	3.5 (3.0, 6.5)	0.265
S_VO₂ (%)	67.5 (61.8, 72.9)	68.7 (63.5, 72.9)	64.3 (60.2, 73.4)	0.094

Results are expressed as median (interquartile ranger). Mann–Whitney U test was used for continuous variables
Abbreviations: RHC right heart catheterization, mPAP mean pulmonary arterial pressure, PAWP pulmonary arterial wedge pressure, PVR pulmonary vascular resistance, WU Wood units, CI cardiac index, RAP right arterial pressure, S_VO₂ mixed venous oxygen saturation
^*P-value < 0.05 is shown in bold

ISSN: 1478-6362