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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Preosteoclast plays a pathogenic role in syndesmophyte formation of ankylosing spondylitis through the secreted PDGFB — GRB2/ERK/RUNX2 pathway

Fig. 1

Cytokines detected in AS patients and healthy controls. A Top pathway enrichment according to the InterPro database. B Differential expression of six cytokines in AS and healthy controls in validation I stage. C Differential expression of PDGFB in Chinese AS patients and healthy controls in the validation II stage. AS-1 represents the 40 AS patients at baseline in the validation II stage, and AS-2 represents the 60 late-stage AS patients who have had a disease duration longer than 5 years. The expression levels of cytokines were compared by unpaired sample t-tests. *** P < 0.005, ** P < 0.01

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