Fig. 4

Verification of candidate biomarkers. A The statistical graph of fluorescence intensity of 5 proteins based on the 17-plexed customized proteins array and the data have been normalized. (*P<0.05; **P<0,01). B ROC curves using TCN2 (AUC=0.703, P=0.0155) and CST6 (AUC=0.738, P=0.0043), C3 (AUC=0.668, P=0.0921) and C4 (AUC=0.702, P=0.0504) for distinguish NPSLE from SLE. C Multiple proteins were combined into panels in distinguishing NPSLE from SLE, using logistic regression analysis, which indicated the highest diagnostic value of the combination of TCN2 and CST6 with an AUC of 0.814