Fig. 2

Achievement of secondary disease outcomes through 1 year. A CDAI LDA (≤ 10); B CDAI remission (≤ 2.8); C SDAI remission (≤ 3.3); D DAS28-CRP LDA (< 3.2); E DAS28-CRP remission (< 2.6); F RAPID3 LDA (≤ 6); G RAPID3 remission (≤ 3); H HAQ-DI Δ ≥ 0.22. Bars represent analyses of achievement of secondary outcomes as observed. At months 3, 6, 9, and 12, T2T sample size was 106, 93, 87, and 86, and RC sample size was 138, 136, 125, and 123, respectively. CDAI: Clinical Disease Activity Index; CI: confidence interval; DAS28-CRP: Disease Activity Score 28-C-reactive protein; HAQ-DI: Health Assessment Questionnaire-Disability Index; LDA: low disease activity; OR: odds ratio; RAPID3: Routine Assessment of Patient Index Data 3; RC: routine care; SDAI: Simple Disease Activity Index; T2T: treat-to-target