Table 1 Baseline patient and disease characteristics
|  | Treat-to-Target (N = 130) | Routine Care (N = 154) | Total (N = 284) |
|---|---|---|---|
Age (years), mean (SD) | 59.2 ± 11.8 | 60.8 ± 11.4 | 60.1 (11.6) |
Sex, n (%) | |||
 Female | 97 (74.6) | 114 (74.0) | 211 (74.3) |
 Male, | 32 (24.6) | 40 (26.0) | 72 (25.4) |
 Missing | 1 (0.8) | 0 (0.0) | 1 (0.4) |
Race, n (%) | |||
 Caucasian | 112 (86.2) | 148 (96.1) | 260 (91.5) |
 Black or African American | 1 (0.8) | 1 (0.6) | 2 (0.7) |
 Asian | 6 (4.6) | 1 (0.6) | 7 (2.5) |
 Hispanic | 3 (2.3) | 1 (0.6) | 4 (1.4) |
 Native/Aboriginal | 1 (0.8) | 0 (0.0) | 1 (0.4) |
 Other | 6 (4.6) | 3 (1.9) | 9 (3.2) |
 Missing | 1 (0.8) | 0 (0.0) | 1 (0.4) |
Smoking Status, n (%) | |||
 Current | 27 (20.8) | 25 (16.2) | 52 (18.3) |
 Past | 41 (31.5) | 57 (37.0) | 98 (34.5) |
 None | 60 (46.2) | 72 (46.8) | 132 (46.5) |
 Missing | 2 (1.5) | 0 (0.0) | 2 (0.7) |
Disease Characteristics | |||
 RA duration (years) | |||
  Mean ± SD | 7.9 ± 9.6 | 7.5 ± 8.6 | 7.7 ± 9.1 |
 RF status, n (%) | |||
  Negative | 39 (30.0) | 55 (35.7) | 94 (33.1) |
  Positive | 79 (60.8) | 80 (51.9) | 159 (56.0) |
  NA/Unknown/Not done | 12 (9.2) | 19 (12.3) | 31 (10.9) |
 Anti-CCP status, n (%) | |||
  Negative | 32 (24.6) | 41 (26.6) | 73 (25.7) |
  Positive | 48 (36.9) | 42 (27.3) | 90 (31.7) |
  NA/Unknown/Not done | 50 (38.5) | 71 (46.1) | 121 (42.6) |
 CRP status (mg/dl) | |||
  N (%) | 109 (87.9) | 128 (92.8) | 237 (90.5) |
  Mean ± SD | 1.7 ± 2.7 | 2.4 ± 4.3 | 2.1 ± 3.7 |
  Median (IQR) | 0.7 (0.2, 1.7) | 0.9 (0.4, 2.5) | 0.8 (0.3, 2.2) |
 ESR (mm/hr) | |||
  N (%) | 96 (100.0) | 117 (100.0) | 213 (100.0) |
  Mean ± SD | 24.2 ± 20.1 | 22.1 ± 18.9 | 23.0 ± 19.5 |
  Median (IQR) | 19.0 (10.0, 31.5) | 16.0 (9.0, 30.0) | 17.0 (9.0, 30.0) |
 MDGA (VAS 100 mm) | |||
  N (%) | 123 (94.6) | 152 (98.7) | 275 (96.8) |
  Mean ± SD | 64.3 ± 17.3 | 60.2 ± 16.9 | 62.0 ± 17.2 |
 TJC28 | |||
  N (%) | 126 (96.9) | 150 (97.4) | 276 (97.2) |
  Mean ± SD | 9.5 ± 6.1 | 10.0 ± 6.1 | 9.8 ± 6.1 |
 SJC28 | |||
  N (%) | 126 (96.9) | 153 (99.4) | 279 (98.2) |
  Mean ± SD | 7.7 ± 4.7 | 8.2 ± 4.5 | 8.0 ± 4.6 |
 Fatigue (VAS 100 mm) | |||
  N (%) | 124 (95.4) | 150 (97.4) | 274 (96.5) |
  Mean ± SD | 65.7 ± 21.9 | 60.8 ± 25.0 | 63.0 ± 23.7 |
 PtGA (VAS 100 mm) | |||
  N (%) | 126 (96.9) | 150 (97.4) | 276 (97.2) |
  Mean ± SD | 65.0 ± 21.4 | 61.9 ± 22.1 | 63.3 ± 21.8 |
 Pain (VAS 100 mm) | |||
  N (%) | 126 (96.9) | 150 (97.4) | 276 (97.2) |
  Mean ± SD | 66.3 ± 23.4 | 62.0 ± 24.3 | 64.0 ± 24.0 |
 HAQ-DI | |||
  N (%) | 125 (96.2) | 151 (98.1) | 276 (97.2) |
  Mean ± SD | 1.5 ± 0.6 | 1.5 ± 0.6 | 1.5 ± 0.6 |