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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Intra-articular delivery of an indoleamine 2,3-dioxygenase galectin-3 fusion protein for osteoarthritis treatment in male Lewis rats

Fig. 1

Joint retention and 4-week post-injection joint distribution for knees injected with NL and NL-Gal3. A The joint residence of NL-Gal3 was significantly longer than the joint residence of unconjugated NL in both MCLT + MMT operated and contralateral joints (p < 0.0001, linear mixed effects model). Data are presented as mean + 95% confidence interval. B Post-mortem analysis of luminescence at 4 weeks after injection demonstrated the presence of NL-Gal3 on the femur, patella/fat pad, meniscus, and tibia of MCLT + MMT operated and contralateral joints. Unconjugated NL was not found

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