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Table 2 The shared genes between significant TWAS genes and DEGs with |log2FC|> 1

From: Identification of candidate genes and chemicals associated with osteoarthritis by transcriptome-wide association study and chemical-gene interaction analysis

OA

Symbol

log2_FC

Adjusted_P-value

Knee

CDK2AP1

1.15

1.49E − 03

EVI2A

1.50

1.93E − 05

GDF5

1.14

2.81E − 02

LTBP1

1.37

2.21E − 03

SPAG4

 − 1.02

2.68E − 04

WWP2

 − 1.36

7.46E − 05

  1. TWAS Transcriptome-wide association study, DEGs Differentially expressed genes, OA Osteoarthritis, FC Fold change