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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Low-dose xenogeneic mesenchymal stem cells target canine osteoarthritis through systemic immunomodulation and homing

Fig. 4

Representation of the results of the MLR assay, functional crossmatch assay, ELISA results, and biodistribution study. A MLR assay with negative control (PBMCs alone), positive control (stimulated PBMCs), co-culture (PBMCs + MSCs), and stimulated co-culture (stimulated PBMCs + MSCs). B Functional crossmatch assay evaluating humoral IgG immune response. C PGE2 concentration in MLR supernatants. D Hyaluronic acid (ng/mL) in canine serum corrected for baseline values. E PGE2 (ng/mL) in canine serum corrected for baseline values. F Biodistribution of 99mTc-labeled MSCs in healthy and injured stifle. All data presented as mean ± SD. The boxplots present the 1st quartile, the 3rd quartile, and the median. In addition, outliers and extreme values are displayed

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Arthritis Research & Therapy

ISSN: 1478-6362

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