Fig. 2

RA gene expression signatures at the pre-pregnancy baseline. A A total of 448 protein-coding genes and 137 lncRNAs were differentially expressed (FDR < 0.05, fold change [FC] ≥ 1.5) between the RA_improved and RA_worsened women at the pre-pregnancy baseline, as shown in the volcano plot. B When T0 expression profiles of each of the RA groups were compared to that of the same 13 healthy women, the RA-associated gene expression signatures observed showed little overlap with each other. Only 42 coding genes, 24 lncRNAs, and 1 miRNA were common to both “RA signatures”