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Table 2 Multivariable linear regression models investigating influencing factors on BASFI in patients with r-axSpA

From: Physical function and sex differences in radiographic axial spondyloarthritis: a cross-sectional analysis on Bath Ankylosing Spondylitis Functional Index

 

Model 1 All patients

Model 2 All patients

(mSASSS)

Model 3 All patients

(BASMI)

Model 2, Males

(mSASSS)

Model 3, Males

(BASMI)

 

Model 2, Females

(mSASSS)

Model 3, Females

(BASMI)

 

R2

0.53

 

0.58

0.61

 

0.62

0.63

 

0.54

0.60

 
 

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

Constant

 − 4.02 (− 5.56 to − 2.48)

 < 0.001

 − 3.89 (− 5.40 to − 2.39)

 < 0.001

 − 3.56 (− 5.00 to − 2.11)

 < 0.001

 − 2.85 (− 4.46 to − 1.23)

 < 0.001

 − 2.90 (− 4.62 to − 1.34)

 < 0.001

 − 4.62 (− 7.18 to − 2.06)

 < 0.001

 − 3.77 (− 6.15 to − 1.38)

0.002

Age, years

0.03 (0.01 to 0.05)

0.003

0.06 (0.04 to 0.08)

 < 0.001

0.03 (0.01 to 0.05)

 < 0.001

0.05 (0.03 to 0.07)

 < 0.001

0.03 (0.01 to 0.06)

0.008

0.08 (0.05 to 0.11)

 < 0.001

0.03 (− 0.01 to 0.07)

0.09

BMI, kg/m2

0.05 (0.01 to 0.10)

0.022

0.05 (0.01 to 0.09)

0.024

0.04 (− 0.00 to 0.08)

0.065

0.04 (− 0.01 to 0.09)

0.093

0.04 (− 0.01 to 0.08)

0.16

0.05 (− 0.03 to 0.13)

0.21

0.04 (− 0.04 to 0.11)

0.35

ASDAS CRP, score

1.73 (1.48 to 1.98)

 < 0.001

1.04 (0.74 to 1.34)

 < 0.001

1.03 (0.75 to 1.32)

 < 0.001

0.84 (0.48 to 1.20)

 < 0.001

0.84 (0.49 to 1.19)

 < 0.001

1.39 (0.86 to 1.93)

 < 0.001

1.36 (0.86 to 1.86)

 < 0.001

BASMI, score

0.58 (0.41 to 0.74)

 < 0.001

N/A

 

0.57 (0.42 to 0.72)

 < 0.001

NA

 

0.52 (0.35 to 0.69)

 < 0.001

NA

 

0.75 (0.43 to 1.06)

 < 0.001

mSASSS, score

NA

 

0.03 (0.02 to 0.04)

 < 0.001

NA

 

0.03 (0.02 to 0.05)

 < 0.001

N/A

 

0.02 (− 0.01 to 0.06)

0.12

NA

 

Fatigue, score

NA

 

0.34 (0.24 to 0.43)

 < 0.001

0.32 (0.23 to 0.42)

 < 0.001

0.41 (0.29 to 0.53)

 < 0.001

0.41 (0.29 to 0.52)

 < 0.001

0.27 (0.11 to 0.42)

0.001

0.22 (0.08 to 0.37)

0.003

Tenderness, score

NA

 

0.17 (0.07 to 0.26)

0.001

0.13 (0.04 to 0.22)

0.006

0.14 (0.02 to 0.27)

0.027

0.10 (− 0.02 to 0.22)

0.10

0.18 (0.02 to 0.34)

0.027

0.15 (0.01 to 0.29)

0.04

Female sex

0.62 (0.17 to 1.06)

0.006

0.28 (− 0.17 to 0.74)

0.22

0.202 (− 0.22 to 0.62)

0.34

NA

NA

 

NA

NA

 
  1. The outcome of the models is 10 percentiles of Bath Ankylosing Spondylitis Functional Index. Models 1–3 include all patients; models 2–3 are consecutively performed in the cohort separated by sex. Highlighted in bold are p-values ≤ 0.05
  2. BASFI Bath Ankylosing Spondylitis Functional Index, r-axSpA radiographic axial spondyloarthritis, R2 coefficient of determination, B unstandardized regression coefficient, CI confidence interval, BMI body mass index, ASDAS Ankylosing Spondylitis Disease Activity Score, CRP C-reactive protein, BASMI Bath Ankylosing Spondylitis Metrology Index, mSASSS Modified Stoke Ankylosing Spondylitis Spinal Score, Fatigue Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) question (QN)1, Tenderness BASDAI QN4