Fig. 5

QRT-PCR validation and ROC analysis of selected DE-lncRNAs and DE-mRNAs in serum exosomes. A Validation of DE-lncRNAs (MIR3945HG-202, NONHSAT193357.1, and NONHSAT190641.1) and DE-mRNAs (CCL5, PFKP, and MPIG6B) in serum exosomes of patients with RA, healthy controls, and patients with OA by qRT-PCR. B ROC curves of the DE-lncRNAs and DE-mRNAs in differentiating patients with RA from healthy controls or patients with OA. ROC, receiver operating characteristic; DE-lncRNAs, differentially expressed lncRNAs; DE-mRNAs, differentially expressed mRNAs; RA, rheumatoid arthritis; OA, osteoarthritis