Table 3 Univariable and multivariable logistic regression analysis with multiple imputation
Univariate | Multivariate | |||||||
|---|---|---|---|---|---|---|---|---|
Complete cases (n = 409) | Multiple imputation (n = 704) | |||||||
Conventional cardiovascular risk factors alone (model 1) | The addition of anti-β2GPI/HLA-DR antibody status (model 2) | The addition of anti-β2GPI/HLA-DR antibody status (model 2) | ||||||
Variables | OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value |
Age | 1.02 (1.00–1.03) | 0.050 | 1.02 (1.00–1.04) | 0.043 | 1.03 (1.00–1.05) | 0.027 | 1.01 (0.99–1.03) | 0.059 |
Disease duration | 1.01 (0.99–1.03) | 0.341 | 1.00 (0.98–1.03) | 0.790 | 1.00 (0.98–1.03) | 0.850 | 1.00 (0.98–1.02) | 0.610 |
Body mass index | 1.04 (0.97–1.10) | 0.270 | 1.02 (0.95–1.09) | 0.651 | 1.01 (0.94–1.09) | 0.730 | 1.01 (0.94–1.08) | 0.750 |
Pack-year smoking | 1.04 (1.02–1.07) | 0.002 | 1.03 (1.00–1.07) | 0.063 | 1.03 (1.00–1.07) | 0.073 | 1.04 (1.01–1.07) | 0.007 |
Current doses of prednisolone | 1.07 (1.01–1.13) | 0.014 | 1.11 (1.02–1.20) | 0.012 | 1.11 (1.03–1.20) | 0.009 | 1.07 (1.01–1.13) | 0.018 |
Dyslipidemia | 1.13 (0.68–1.89) | 0.632 | 0.73 (0.35–1.49) | 0.387 | 0.78 (0.37–1.61) | 0.500 | 0.77 (0.42–1.40) | 0.401 |
Arterial hypertension | 2.54 (1.56–4.16) | < 0.001 | 1.82 (0.93–3.58) | 0.081 | 1.81 (0.91–3.61) | 0.092 | 2.37 (1.33–4.23) | 0.003 |
Diabetes | 1.62 (0.83–3.17) | 0.155 | 1.04 (0.42–2.56) | 0.932 | 1.26 (0.51–3.12) | 0.620 | 1.15 (0.52–2.52) | 0.723 |
Anti-β2GPI/HLA-DR antibody status (cut-off = 172.359 U/ml) | 5.10 (2.94–8.87) | < 0.001 | — | — | 4.39 (2.14–9.03) | < 0.001 | 5.13 (2.85–9.24) | < 0.001 |