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Table 1 Baseline characteristics of the study population

From: Systemic sclerosis and risk of bronchiectasis: a nationwide longitudinal cohort study

 

Total (N = 29,070)

Systemic sclerosis cohort (n = 4845)

Matched cohort (n = 24,225)

P value

Male sex

4422 (15.2)

737 (15.2)

3685 (15.2)

> 0.999

Age, years

53.5 ± 12.6

53.4 ± 12.6

53.5 ± 12.6

> 0.999

 20–39

4050 (13.9)

675 (13.9)

3375 (13.9)

 

 40–64

19,338 (66.5)

3223 (66.5)

16,115 (66.5)

 

 ≥ 65

5682 (19.6)

947 (19.6)

4735 (19.6)

 

Extra-pulmonary comorbidities

 Diabetes mellitus

2355 (8.1)

389 (8.0)

1966 (8.1)

0.840

 Hypertension

8411 (28.9)

2562 (52.9)

5849 (24.1)

< 0.001

 Dyslipidemia

4836 (16.6)

922 (19.0)

3914 (16.2)

< 0.001

 ESRD

88 (0.3)

35 (0.7)

53 (0.2)

< 0.001

 IHD

1991 (6.8)

720 (14.7)

1271 (5.3)

< 0.001

 CHF

539 (1.8)

231 (4.8)

308 (1.3)

< 0.001

Pulmonary comorbidities

 COPD

2516 (8.6)

959 (19.8)

1557 (6.4)

< 0.001

 Asthma

3341 (11.5)

901 (18.6)

2440 (10.1)

< 0.001

 Previous pulmonary tuberculosis

52 (0.2)

24 (0.5)

28 (0.1)

< 0.001

CTDs other than systemic sclerosis

558 (1.9)

472 (9.7)

86 (0.4)

< 0.001

 Rheumatoid arthritis

200 (0.7)

127 (2.6)

73 (0.3)

< 0.001

 Systemic lupus erythematous

246 (0.8)

234 (4.8)

12 (0.1)

< 0.001

 Dermatomyositis

27 (0.1)

27 (0.6)

0 (0)

< 0.001

 Mixed connective tissue disease

112 (0.4)

112 (2.3)

0 (0)

< 0.001

 Polymyalgia rheumatica

2 (0.01)

1 (0.02)

1 (0)

0.206

  1. Data are presented as number (percentage) or mean ± standard deviation. CTDs other than systemic sclerosis were rheumatoid arthritis, systemic lupus erythematous, dermatomyositis, mixed connective tissue disease, or polymyalgia rheumatica
  2. Abbreviations: ESRD End-stage renal disease, IHD Ischemic heart disease, CHF Congestive heart failure, COPD Chronic obstructive lung disease, CTD Connective tissue disease