Fig. 4

a Physician- and patient-reported outcomes over time: NRS, numeric rating scale; C-HAQ, childhood- health assessment questionnaire; PGDA, physician global disease activity. Data shown by means with 95% confidence interval of the mean (95% CI C-HAQ: inclusion 0.23–0.31; 1 YFU 0.13–0.21; 2 YFU 0.10–0.19; 3 YFU 0.13–0.28; 4 YFU 0.07–0.23). b Number of patients with favorable outcomes. Physician global disease activity (PGDA) NRS < 1, patient pain NRS < 1, patient overall well-being NRS < 1, and C-HAQ = 0 (childhood health assessment questionnaire)) from inclusion to 4 years of follow-up; percentages of patients are given, who reached the proposed levels of remission. OR, odds ratio