Rheumatoid arthritis increases the risk of malignant neoplasm of bone and articular cartilage: a two-sample bidirectional mendelian randomization study

Table 1 Sensitivity analysis of the MR analysis results of exposures and outcomes

Exposure	Outcome	Heterogeneity		Pleiotropy	MR-PRESSO		MR-RAPS
		Cochran’s Q test (IVW)	Rucker’s Q test (MR-Egger)	Intercept test (MR-Egger)	Outlier test	Pleiotropy test	Normal Distribution
		P value	P value	P value	Number	P value	P value
RA	BNBAC	0.184	0.167	0.720	0	0.152	0.698
RA	MNBAC	0.830	0.809	0.893	0	0.819	0.384
BNBAC	RA	0.500	0.403	0.901	0	0.510	0.973
MNBAC	RA	0.053	0.034	0.847	0	0.338	0.840

MR mendelian randomization, RA rheumatoid arthritis, BNBAC benign neoplasm of bone and articular cartilage, MNBAC malignant neoplasm of bone and articular cartilage

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