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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Prokineticin 2 is a catabolic regulator of osteoarthritic cartilage destruction in mouse

Fig. 2

Prok2 stimulates expression of MMP3 and MMP13 in chondrocytes. A, B RT-PCR (A) and qRT-PCR (B) of the indicated molecules in chondrocytes infected with 800 MOI of Ad-C or the indicated MOI of Ad-Prok2 for 36 h (n=7 cell cultures). C, D RT-PCR (C) and qRT-PCR (D) of the indicated molecules in chondrocytes treated with vehicle alone or the indicated amount of recombinant Prok2 (rProk2) for 36 h (n=8 cell cultures). Values are presented as mean ± 95% CI, and significance was evaluated by paired t-test

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