Skip to main content

Table 2 Prognostic factors of death in MPA patients

From: Risk prediction model for mortality in microscopic polyangiitis: multicentre REVEAL cohort study

 

Unadjusted

Age-adjusted

Risk factors

Crude HR

95% CI

P

Adjusted HR

95% CI

P

Age (by year)

1.110

1.072–1.151

<0.001

   

Smoking index

1.080

0.974–1.174

0.135

   

Alb (g/dL)

1.001

0.999–1.001

0.054

   

CRP (mg/dL)

1.038

0.995–1.083

0.084

   

BVAS at onset

1.062

1.029–1.095

<0.001

1.054

1.021–1.087

0.001

Five-Factor Score 2009

 2 (ref; ≤1)

4.308

1.865–12.506

<0.001

2.054

0.799–5.277

0.135

 ≥3 (ref; ≤1)

3.578

1.339–11.217

0.010

1.541

0.538–4.412

0.42

 ≥3 (ref; 2)

0.830

0.428–1.507

0.5535

   

EUVAS categorization system

 Early systemic (ref; localized)

2.932

0.575–53.477

0.23

   

 Systemic (ref; localized)

2.369

0.507–42.202

0.329

   

 Severe (ref; localized)

4.692

0.959–84.637

0.058

   

 Systemic (ref; early systemic)

0.808

0.423–1.644

0.54

   

 Severe (ref; early systemic)

1.600

0.765–3.452

0.213

   

 Severe (ref; systemic)

1.981

1.066–3.560

0.031

2.725

1.463–5.076

0.002

  1. HR Hazard ratio, CI Confidence interval, ref Reference, MPA, Microscopic polyangiitis, Alb albumin, CRP C-reactive protein, BVAS Birmingham Vasculitis Activity Score, EUVAS European Vasculitis Study Group
  2. The hazard ratios of death due to infection were derived from univariable and multivariable Cox regression analysis