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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: The dual pro-inflammatory and bone-protective role of calcitonin gene-related peptide alpha in age-related osteoarthritis

Fig. 2

αCGRP promotes intraarticular expression of pro-inflammatory and catabolic cartilage markers in OA-affected knee joints. A qRT-PCR gene expression analysis of inflammation markers, B catabolic/hypertrophic cartilage/bone turnover markers, and C anabolic cartilage/bone turnover markers in knee joint samples of indicated groups. Given values are median ± minimum and maximum. Values for WTaged and αCGRP.−/−aged mice are shown as relative fold changes with respect to CTRL groups that were set to 1

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