Fig. 2

Effects of pExo in chondrocytes. A In vitro study scheme to determine the impacts of pExo on chondrocytes. B WST-1 assay to compare the impacts of 10% FBS, PDGF (100 ng/ml), or pExo (N = 3 donors, 50 µg/ml) on chondrocyte proliferation. Data is presented as mean ± 95% CI (t-test, vs basal medium condition, *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.0001). C Traswell migration assay to evaluate the effects of 10% FBS, FGF-2 (100 ng/ml), or pExo (N = 3 donors, 200 µg/ml) for chondrocyte migration. Data is presented as mean ± 95% CI (t-test, vs 10% FBS condition, *P < 0.05, **P < 0.01, ****P < 0.0001)