Table 3 Breakdown of differentially expressed genes with q < 0.05, |fold change| ≥ 1.5 (N = 53 total genes)
Category | Genes |
|---|---|
Ligand/receptor binding, signaling, chemotaxis | Non-degenerated: KAZALD1 Degenerated: BMPR1B, NTN1, NPR3, SAMD9L |
Signal transduction (GPRC, 2nd messengers, etc.) | Non-degenerated: ---- Degenerated: ADGRL4, PSD3 |
Intracellular and/or membrane transport | Non-degenerated: TRPV2 Degenerated: FAM155A, SCN8A, SLC7A8, SLC9A7, EEA1, VPS13C, DYNC2H1, KIAA1109, ABCC5, PKD2, CEP290 |
Transcription, RNA-binding, and translation regulation | Non-degenerated: FOXF2 Degenerated: KLF12, CPEB2, GABPB1-AS1, LINC01547, LINC00342, ATRX, CHD9 |
Metabolism, proliferation, differentiation, and cell cycle | Non-degenerated: ENO1, PRRX2, TST, MPST, GALE, S100A2, ID4 Degenerated: ---- |
Cytoskeleton, ECM, and cell/matrix adhesion | Non-degenerated: HAPLN1, LGALS1 Degenerated: DSG3, THSD4, DST, TMOD2, ADAMTS5, CEMIP, ITGAV, FMN1, FAT3, EMB, AKAP9 |
Proteolysis, protein-binding, and protein modification activity | Non-degenerated: ---- Degenerated: SULF1 |
Immunogenic, inflammatory, and stress function | Non-degenerated: CYBA, CPVL Degenerated: ---- |
Unclear function | Non-degenerated: AL450405.1 Degenerated: KIAA1549L, NAALADL2 |