Fig. 6

Joint remobilization ameliorates synovial sensory innervation in mice after short-term immobilization in mice. A Representative images of H/E staining images in knee joints from control, immobilization for 2 weeks, remobilization after 2-week immobilization. Scale bar, 50 mm. B Representative images of IF staining of CGRP staining (first row), DAPI staining (second row) and merge image (third row) in synovial tissue of knee joints of the indicated groups. The white dashed lines indicate the synovial tissue. Scale bar, 50 mm. C Quantitative data of expression of CGRP based on staining results in B. N = 6 biologically independent replicates per group. Results were expressed as mean ± standard deviation (sd). **P < 0.01. IB, immobilization; RB, remobilization