Fig. 4
From: Wilforine inhibits rheumatoid arthritis pathology through the Wnt11/β-catenin signaling pathway axis
WFR inhibits abnormally elevated Wnt11 expression in RA. RT-qPCR results showed that WFR reduced mRNA levels of abnormally elevated Wnt11 in RA FLS (A), CIA rat synovium (B), and CIA FLS (C). Immunofluorescence results showed that WFR significantly reduced the amount of Wnt11 protein in RA FLS (D) (scale bar = 50 μm) and CIA FLS (E) (scale bar = 50 μm). *RA/CIA group vs normal, #RA/CIA group+WFR vs RA/CIA group, n = 3. *p < 0.01