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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Exosome-mediated delivery of super-repressor IκBα alleviates inflammation and joint damages in rheumatoid arthritis

Fig. 3

Exo-srIκB suppresses inflammatory cytokines in both PBMCs and SFMCs obtained from patients with rheumatoid arthritis. AB Flow cytometry analysis was performed to assess the percentages of IL-17A and GM-CSF-positive cells in PBMCs and SFMCs. CD ELISA was conducted to measure TNF-α, IL-17A, IL-6, and GM-CSF levels in ex vivo supernatants from PBMCs and SFMCs. Statistical significance was determined using the Wilcoxon matched-pairs signed-rank test. The symbols represent individual sample. NS, not significant. *P < 0.05

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