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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Efficient delivery of the lncRNA LEF1-AS1 through the antibody LAIR-1 (CD305)-modified Zn-Adenine targets articular inflammation to enhance the treatment of rheumatoid arthritis

Fig. 1

The function of LEF1-AS1 in the HFLS cells. A–C LEF1-AS1, miR-30-5p, and PIK3R2 mRNA expression in 24 pairs of RA synovial tissues and matched normal synovial tissues. D–E Immunoblot showing relative expression of PIK3R2 protein. F Expression levels of LEF1-AS1, miR-30-5p, and PIK3R2 in TNF-α-induced RASFs. G Viability of the HFLS cells treated for 0, 24, or 48 h. H–J Proliferative capacity of the HFLS cells transfected with LEF1-AS1 measured by cell counting assay, H&E staining, and colony formation assay. K Invasion of HFLS cells was detected by the transwell assay (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)

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Arthritis Research & Therapy

ISSN: 1478-6362

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