Table 2 Pharmacokinetic parameters using non-compartmental analysis
From: In vivo study of newly developed albumin-conjugated urate oxidase for gout treatment
Parameters | Rasburicase (2.0 mg/kg) | Pegloticase (2.0 mg/kg) | PAT101 (6 mg/kg) |
|---|---|---|---|
T1/2 (hr) | 2.03 ± 0.48 | 38.59 ± 11.11 | 31.81 ± 11.31 |
AUClast (h*mU/mL) | 951.73 ± 169.99 | 3110.87 ± 550.31 | 4891.35 ± 1065.23 |