Table 3 Pharmacokinetic parameters using non-compartmental analysis
From: In vivo study of newly developed albumin-conjugated urate oxidase for gout treatment
Parameter | PAT101 (1 mg/kg) | Pegloticase (2 mg/kg) |
|---|---|---|
T1/2 (hr) | 95.02 ± 12.56 | 45.23 ± 9.18 |
Tmax (hr) | 0.50 ± 0.00 | 0.50 ± 0.00 |
Cmax (mU/mL) | 166.05 ± 14.02 | 176.37 ± 23.60 |
AUClast (h*mU/mL) | 18,067.84 ± 1577.39 | 14,365.17 ± 1901.47 |