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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Causal relationship between systemic lupus erythematosus and primary liver cirrhosis based on two-sample bidirectional Mendelian randomization and transcriptome overlap analysis

Fig. 1

MR estimation of genetic reliability between SLE and PBC. (A-B) Scatter plots. The estimation effect of MR methods with slope. Bilateral MR analysis showed that both IVW methods were high-risk factors for SLE or PBC. (C-D) Funnel plots. Cochran Q-test showed heterogeneity in the results of bidirectional MR analysis. (E-F) Leave-one-out plots. The black dots were used by the IVW method to evaluate causal effects and excluded individual analyses one by one. The red dot indicates the use of IVW for all SNPs. Bidirectional sensitivity testing verified the robustness of MR analysis

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Arthritis Research & Therapy

ISSN: 1478-6362

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