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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Monocyte-derived transcriptomes explain the ineffectiveness of abatacept in rheumatoid arthritis

Fig. 2

Transcriptomic analysis of the current study. A, B Volcano plots showing differentially expressed genes between responders and non-responders before treatment (A) and three months after treatment (B). C Results of gene set enrichment analysis before treatment. D Correlation between each gene’s expressions. The number in each box represents the Pearson's correlation coefficient. E Expression was standardized across all samples, and Z scores were shown. Sample names beginning with “R” indicate responders, “NR” indicates non-responders; sample names ending with “0 M” indicate pre-treatment, and “_3M” indicates 3 months post-treatment. F Results of cell type enrichment analysis before treatment. T, T cell; NK, NK cell; B. B cell; DC. dendritic cell; Mono, monocyte. G Estimated gene expression in monocytes. As in E, Z scores are shown

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