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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: ADAM8 silencing suppresses the migration and invasion of fibroblast-like synoviocytes via FSCN1/MAPK cascade in osteoarthritis

Fig. 2

ADAM8 is up-regulated in FLSs after treatment with IL-1β. A, D Wound healing assays and quantitative analysis of the migration abilities of FLSs with different concentrations of IL-1β. B, E Transwell assays and quantitative analysis of the migration ability of FLSs with different concentrations of IL-1β. C, F Transwell assays and quantitative analysis of the invasion abilities of FLSs with different concentrations of IL-1β. G Western blot and quantitative analysis of IL-6, TNF-α, and COX-2 in FLSs after treatment with IL-1β. H-J qRT-PCR analysis of the mRNA expression levels of IL-6, TNF-α, and COX2. K qRT-PCR analysis of the mRNA expression levels of ADAM8. L Immunofluorescence staining of ADAM8 in FLSs. Scale bar = 200 µm. *P < 0.05; **P < 0.01

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Arthritis Research & Therapy

ISSN: 1478-6362

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