Fig. 3

The expression of ADAM8 was found to be increased in the synovium of patients with OA. A H&E staining of synovial tissues in ACL injury and OA patients. B-D TNF-α, IL-1β, and ADAM8 IHC staining of synovial tissues in ACL injury and OA patients. E–G Quantification of IHC staining for TNF-α, IL-1β, and ADAM8. Scale bars, 100 µm. **P < 0.01