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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Proteomic profiling identifies SPP1 associated with rapidly progressive interstitial lung disease in anti-MDA5-positive dermatomyositis

Fig. 1

Differentially expressed proteins (DEPs) in MDA5+ DM and MDA5+ DM with RP-ILD samples. A, D Volcano plots depicted DEPs in comparison of MDA5+ DM versus HC, and MDA5+ DM with RP-ILD versus non-RP-ILD, respectively. The screening criteria were p < 0.05. B, E PCA cluster plots showed the overall distribution of HC and MDA5+ DM samples, and MDA5+ DM RP-ILD and non-RP-ILD samples. C, F Heatmaps showed the top 50 DEPs in comparisons of MDA5+ DM versus HC, and MDA5+ DM with RP-ILD versus non-RP-ILD, respectively. HC, healthy control

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