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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Autoimmune congenital heart block: a case report and review of the literature related to pathogenesis and pregnancy management

Fig. 1

The potential pathogenesis of autoimmune congenital heart block and its prevention and treatment. A Accumulation of apoptotic cardiomyocytes, inflammation, extensive fibrosis, calcification, and scarring play an important role in the induction of ACHB. B Antibodies may disturb the electrical activity of cardiomyocytes in the conduction system through dysregulating intracellular calcium homeostasis. C Management in pregnant women with positive anti-Ro/SSA and/or anti-La/SSB antibodies or rheumatic diseases during pregnancy. D Treatment for ACHB fetuses

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Arthritis Research & Therapy

ISSN: 1478-6362

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