Fig. 4From: Management and treatment outcomes of rheumatoid arthritis in the era of biologic and targeted synthetic therapies: evaluation of 10-year data from the KURAMA cohortMixed-effect model fitted to the annual change in disease activity and functional disability. A–C The dots denote the observed median values, and the lines represent the regression line fitted using mixed-effect models. A DAS28-CRP. B CDAI. C HAQBack to article page