Fig. 4

The identification of the differentially abundant gut microbiota in RA and the relationship of the gut microbiota dysbiosis with RA. A The phylogenetic distribution in cladogram of differential gut microbiota between RA and HCs. B The differential gut microbiota with LDA score > 4 and P < 0.05 between RA and HCs, and Ruminococcus 2 was the differential gut microbiota with the highest LDA score at the genus level in RA. C The correlation heatmap of the differentially abundant gut microbiota and the disease activity of RA. D The ROC curve of biomarker analysis for Ruminococcus 2. (The letters c, o, f and g represent class, order, family, and genus, respectively. RA: rheumatoid arthritis; HCs: healthy controls; LDA: linear discriminant analysis; ROC: receiver operating characteristic)