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Table 1 The summary of demographic data, clinical data and laboratory tests

From: Impaired immune tolerance mediated by reduced Tfr cells in rheumatoid arthritis linked to gut microbiota dysbiosis and altered metabolites

 

HC (n = 17)

New-onset RA (n = 32)

P value

Demographic data

 Age (years)a

51.94 ± 13.03

56.78 ± 11.69

0.753

 Sex(male/female)b

4/13

9/23

0.729

Clinical data

 Course(months)c

-

12(3,57)

-

 TJCc

-

9(4,20)

-

 SJCc

-

6(2,18)

-

 DAS28c

-

5.38(4.45,6.97)

-

Laboratory tests

 ESR (mm/h)c

-

58.50(31.00,84.50)

-

 Anti-CCP (U/ml)c

-

124.37(56.71,223.37)

-

 RF-IgM (U/ml)c

-

288.10(59.25,300.00)

-

 RF-IgG (U/ml)c

-

106.30(38.2,196.20)

-

  1. Abbreviations: HC healthy control, RA rheumatoid arthritis, TJC tenderness joint count, SJC swollen joint count, DAS 28 Disease Activity Score 28, ESR erythrocyte sedimentation rate, anti-CCP anti-cyclic peptide containing citrulline, RF rheumatoid factor
  2. aResults were expressed as the mean ± SD and were analyzed by independent samples t-tests
  3. bCategorical variables were described as rates and percentages and were assessed using the chi-square or Fisher’s exact tests
  4. cResults were expressed as the median (Q1, Q3) and were analyzed by Mann–Whitney U test