Table 1 Causal effects of immune cells on ankylosing spondylitis
Exposure | Outcome | Method | nSNP | P | OR (95% CI) |
|---|---|---|---|---|---|
HLA DR on CD14 − CD16 + monocyte | Ankylosing spondylitis | Inverse variance weighted | 7 | 1.46E − 04 | 0.669 (0.544,0.823) |
MR-Egger | 7 | 0.100 | 0.499 (0.254,0.982) | ||
Weighted median | 7 | 0.004 | 0.670 (0.550,0.890) | ||
Weighted mode | 7 | 0.0193 | 0.676 (0.531,0.861) | ||
HLA DR on CD33dim HLA DR + CD11b +  | Inverse variance weighted | 3 | 2.12E − 04 | 0.589 (0.446,0.780) | |
MR-Egger | 3 | 0.352 | 0.00000156 (1.45E − 13,16.601) | ||
Weighted median | 3 | 4.75E − 04 | 0.602 (0.452,0.800) | ||
Weighted mode | 3 | 0.074 | 0.607 (0.457,0.805) |