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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Integrative analysis of single-cell and bulk transcriptome data reveal the significant role of macrophages in lupus nephritis

Fig. 3

Results of the multiplexed immunofluorescence assay. (A) Hematoxylin and eosin (HE) staining and immunofluorescence staining targeting CD68 and CD163 in lupus nephritis (LN) tissue samples. (B) The gene expression of CD163 alongside the pseudotime within macrophage subtypes in LN. (C) The stacked violin plots of CD163 and CD68 gene expression in macrophages sub1, 2 and 3 in LN. (D, E, F, G, H) HE staining and immunofluorescence staining targeting CD68 and CD3 as along with DAPI staining in normal kidney tissues (D, E) and LN tissue samples (F, G, H). The LN immunofluorescence images in this figure are from a 39-year-old woman with 1 year of stage IV + V lupus nephritis (LN patient 5 in Supplementary Table 1)

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Arthritis Research & Therapy

ISSN: 1478-6362

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