Volume 13 Supplement 1

The evolution of anti-TNF therapy in rheumatic disease: experience, insights and advances


Edited by Joachim Kalden

Publication of this supplement is sponsored by Merck & Company, Inc, Whitehouse Station, New Jersey, USA.

  1. Review

    Infliximab: 12 years of experience

    Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) are immune-mediated conditions that share an inflammatory mechanism fuelled by excessive cytokines, particularly TNF. Contro...

    Josef S Smolen and Paul Emery

    Arthritis Research & Therapy 2011 13(Suppl 1):S2

    Published on: 25 May 2011

  2. Review

    Understanding emerging treatment paradigms in rheumatoid arthritis

    Treatment strategies for rheumatoid arthritis (RA) will continue to evolve as new drugs are developed, as new data become available, and as our potential to achieve greater and more consistent outcomes becomes...

    Ferdinand C Breedveld and Bernard Combe

    Arthritis Research & Therapy 2011 13(Suppl 1):S3

    Published on: 25 May 2011

  3. Review

    Structural damage in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: traditional views, novel insights gained from TNF blockade, and concepts for the future

    Structural changes of bone and cartilage are a hallmark of inflammatory joint diseases such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). Despite certain similaritie...

    Georg Schett, Laura C Coates, Zoe R Ash, Stefanie Finzel and Phillip G Conaghan

    Arthritis Research & Therapy 2011 13(Suppl 1):S4

    Published on: 25 May 2011

  4. Review

    Advances in rheumatology: new targeted therapeutics

    Treatment of inflammatory arthritides - including rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis - has seen much progress in recent years, partially due to increased understanding of the...

    Paul P Tak and Joachim R Kalden

    Arthritis Research & Therapy 2011 13(Suppl 1):S5

    Published on: 25 May 2011