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  1. Follicular helper T (Tfh) cells are specialized in helping B lymphocytes, which play a central role in autoimmune diseases that have a major B cell component, such as in rheumatoid arthritis (RA). Follicular r...

    Authors: Qian Niu, Zhuo-chun Huang, Xiao-juan Wu, Ya-xiong Jin, Yun-fei An, Ya-mei Li, Huan Xu, Bin Yang and Lan-lan Wang
    Citation: Arthritis Research & Therapy 2018 20:200
  2. Although exercise is an effective treatment for fibromyalgia, the relationships between lifestyle physical activity and multiple symptomology domains of fibromyalgia are not clear. Thus, the purpose of this st...

    Authors: Ericka N. Merriwether, Laura A. Frey-Law, Barbara A. Rakel, Miriam B. Zimmerman, Dana L. Dailey, Carol G. T. Vance, Meenakshi Golchha, Katherine M. Geasland, Ruth Chimenti, Leslie J. Crofford and Kathleen A. Sluka
    Citation: Arthritis Research & Therapy 2018 20:199
  3. We aimed to investigate the efficacy of abatacept in preclinical mouse models of digestive involvement, pulmonary fibrosis, and related pulmonary hypertension (PH), mimicking internal organ involvement in syst...

    Authors: Gonçalo Boleto, Christophe Guignabert, Sonia Pezet, Anne Cauvet, Jérémy Sadoine, Ly Tu, Carole Nicco, Camille Gobeaux, Frédéric Batteux, Yannick Allanore and Jérôme Avouac
    Citation: Arthritis Research & Therapy 2018 20:197
  4. This study aimed to determine whether, besides carotid ultrasound (US), a lateral lumbar spine radiography may also help identify ankylosing spondylitis (AS) patients at high risk of cardiovascular (CV) disease.

    Authors: Javier Rueda-Gotor, Fernanda Genre, Alfonso Corrales, Ricardo Blanco, Patricia Fuentevilla, Virginia Portilla, Rosa Expósito, Cristina Mata, Trinitario Pina, Carlos González-Juanatey, Luis Rodriguez-Rodriguez and Miguel A. González-Gay
    Citation: Arthritis Research & Therapy 2018 20:195
  5. Cardiovascular disease is a leading cause of death in ANCA-associated vasculitis (AAV). An expansion of CD4+CD28null T cells is seen mainly in cytomegalovirus (CMV)-seropositive individuals and has been linked to...

    Authors: Dimitrios Chanouzas, Michael Sagmeister, Lovesh Dyall, Phoebe Sharp, Lucy Powley, Serena Johal, Jessica Bowen, Peter Nightingale, Charles J. Ferro, Matthew D. Morgan, Paul Moss and Lorraine Harper
    Citation: Arthritis Research & Therapy 2018 20:194
  6. Type III interferons (IFNs) or IFN-λs are the newly discovered cytokines that primarily target the cells of epithelial and myeloid lineages, which are major components of kidneys. The current study aimed to in...

    Authors: Ji-Yih Chen, Chin-Man Wang, Tai-Di Chen, Yeong-Jian Jan Wu, Jing-Chi Lin, Ling Ying Lu and Jianming Wu
    Citation: Arthritis Research & Therapy 2018 20:193
  7. Gout is an inflammatory arthritis caused by monosodium urate monohydrate (MSU) crystals’ joint deposition. MSU phagocytosis by resident macrophages is a key step in gout pathogenesis. MSU phagocytosis triggers...

    Authors: Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Wendy Wong, Anthony M. Reginato, Changqi Sun, Tannin A. Schmidt and Khaled A. Elsaid
    Citation: Arthritis Research & Therapy 2018 20:192
  8. Therapeutic targeting of tumour necrosis factor (TNF)-α is highly effective in ankylosing spondylitis (AS) patients. However, since one-third of anti-TNF-treated AS patients do not show an adequate clinical re...

    Authors: Ursula Schulte-Wrede, Till Sörensen, Joachim R. Grün, Thomas Häupl, Heike Hirseland, Marta Steinbrich-Zöllner, Peihua Wu, Andreas Radbruch, Denis Poddubnyy, Joachim Sieper, Uta Syrbe and Andreas Grützkau
    Citation: Arthritis Research & Therapy 2018 20:191
  9. Hyperuricemia (HU) is in the causal pathway for developing clinical gout. There are few population-based assessments of the absolute and relative risk of clinically diagnosed incident gout in subjects with HU....

    Authors: Meliha C. Kapetanovic, Peter Nilsson, Carl Turesson, Martin Englund, Nicola Dalbeth and Lennart Jacobsson
    Citation: Arthritis Research & Therapy 2018 20:190
  10. Fibroblast-like synovial cells (FLS) have multilineage differentiation potential including osteoblasts. We aimed to investigate the role of microRNAs during the osteogenic differentiation of rheumatoid arthrit...

    Authors: Naoki Iwamoto, Shoichi Fukui, Ayuko Takatani, Toshimasa Shimizu, Masataka Umeda, Ayako Nishino, Takashi Igawa, Tomohiro Koga, Shin-ya Kawashiri, Kunihiro Ichinose, Mami Tmai, Hideki Nakamura, Tomoki Origuchi, Ko Chiba, Makoto Osaki, Astrid Jüngel…
    Citation: Arthritis Research & Therapy 2018 20:189
  11. Polymyositis (PM) and dermatomyositis (DM) are two distinct subgroups of idiopathic inflammatory myopathies, a chronic inflammatory disorder clinically characterized by muscle weakness and inflammatory cell in...

    Authors: Miranda Houtman, Louise Ekholm, Espen Hesselberg, Karine Chemin, Vivianne Malmström, Ann M. Reed, Ingrid E. Lundberg and Leonid Padyukov
    Citation: Arthritis Research & Therapy 2018 20:188
  12. In systemic sclerosis (SSc), autoantibodies provide the most accurate tool to predict the disease subset and pattern of organ involvement. Scleroderma autoantibodies target nucleic acids or DNA/RNA-binding pro...

    Authors: Elena Raschi, Cecilia Beatrice Chighizola, Laura Cesana, Daniela Privitera, Francesca Ingegnoli, Claudio Mastaglio, Pier Luigi Meroni and Maria Orietta Borghi
    Citation: Arthritis Research & Therapy 2018 20:187
  13. Recent studies have shown a crucial role of Gαq in immune regulation, but how Gαq modulates regulatory B-cell (Breg) function is still unclear. We address this here.

    Authors: Yan He, Xiaoqing Yuan, Yan Li, Chunlian Zhong, Yuan Liu, Hongyan Qian, Jingxiu Xuan, Lihua Duan and Guixiu Shi
    Citation: Arthritis Research & Therapy 2018 20:186
  14. Systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) is one of the leading causes of death in SSc. Identification of a serum-based proteomic diagnostic biomarker for SSc-PAH would allow for ...

    Authors: Lisa M. Rice, Julio C. Mantero, Eric A. Stratton, Rod Warburton, Kari Roberts, Nicholas Hill, Robert W. Simms, Robyn Domsic, Harrison W. Farber and Robert Layfatis
    Citation: Arthritis Research & Therapy 2018 20:185

    The Correction to this article has been published in Arthritis Research & Therapy 2022 24:118

  15. Lack of adequate self-care, frequent admissions, and poor quality of life are common and serious problems in adult patients with systemic lupus erythematosus (SLE). Some studies have revealed that transitional...

    Authors: Xia Xie, Yuqing Song, Hui Yang, Anliu Nie, Hong Chen and Ji-ping Li
    Citation: Arthritis Research & Therapy 2018 20:184
  16. Given the need for early detection of organ involvement in systemic sclerosis, we evaluated 99mTc-rhAnnexin V-128 for the detection of early stages of interstitial lung disease (ILD) in respective animal models u...

    Authors: Janine Schniering, Li Guo, Matthias Brunner, Roger Schibli, Shuang Ye, Oliver Distler, Martin Béhé and Britta Maurer
    Citation: Arthritis Research & Therapy 2018 20:183
  17. Stem cell therapy is considered as a promising alternative to treat intervertebral disc degeneration (IDD). Extensive work had been done on identifying and comparing different types of candidate stem cells, bo...

    Authors: Zhihua Han, Jiandong Wang, Liang Gao, Qiugen Wang and Jianhong Wu
    Citation: Arthritis Research & Therapy 2018 20:182
  18. Thickened skin is a major clinical feature in patients with systemic sclerosis (SSc). We investigated changes of skin thickness in patients with SSc using both high frequency ultrasound (HFU) and the modified ...

    Authors: Hongyan Li, Daniel E. Furst, Hongtao Jin, Chao Sun, Xiaoping Wang, Lin Yang, Jingjing He, Yanru Wang and Aijing Liu
    Citation: Arthritis Research & Therapy 2018 20:181
  19. It is currently impossible to predict the prognosis of patients with juvenile dermatomyositis (JDM). The aim of this study was to find clinical features most strongly associated with outcome variables in JDM a...

    Authors: E. H. Pieter van Dijkhuizen, Maria De Iorio, Lucy R. Wedderburn and Claire T. Deakin
    Citation: Arthritis Research & Therapy 2018 20:180
  20. Ferritin positively associates with serum urate and an interventional study suggests that iron has a role in triggering gout flares. The objective of this study was to further explore the relationship between ...

    Authors: Tahzeeb Fatima, Cushla McKinney, Tanya J. Major, Lisa K. Stamp, Nicola Dalbeth, Cory Iverson, Tony R. Merriman and Jeffrey N. Miner
    Citation: Arthritis Research & Therapy 2018 20:179
  21. This double-blind, randomized, 78-week study evaluated the efficacy, safety, immunogenicity, pharmacokinetics, and pharmacodynamics of PF-06410293, a candidate adalimumab biosimilar, versus adalimumab referenc...

    Authors: Roy M. Fleischmann, Rieke Alten, Margarita Pileckyte, Kasia Lobello, Steven Y. Hua, Carol Cronenberger, Daniel Alvarez, Amy E. Bock and K. Lea Sewell
    Citation: Arthritis Research & Therapy 2018 20:178
  22. Unfortunately, after publication of this article [1], it was noticed that 2 authors were erroneously mentioned as co-first authors

    Authors: Qibin Yang, Quanbo Zhang, Yufeng Qing, Li Zhou, Qingsheng Mi and Jingguo Zhou
    Citation: Arthritis Research & Therapy 2018 20:177

    The original article was published in Arthritis Research & Therapy 2018 20:144

  23. The close temporal association between onset of some connective tissue diseases and cancer suggests a paraneoplastic association. Adult patients with scleroderma with anti-RNA polymerase III autoantibodies and...

    Authors: Zoe E. Betteridge, Lynsey Priest, Robert G. Cooper, Neil J. McHugh, Fiona Blackhall and Janine A. Lamb
    Citation: Arthritis Research & Therapy 2018 20:176
  24. The Mediterranean diet has been associated with lower mortality and lower risk of cardiovascular diseases and cancer. Although its components have been analysed in several studies, only one study has specifica...

    Authors: Kari Johansson, Johan Askling, Lars Alfredsson and Daniela Di Giuseppe
    Citation: Arthritis Research & Therapy 2018 20:175
  25. In the present study, we explored the effects of immediate induction therapy with the anti-tumour necrosis factor (TNF)α antibody infliximab (IFX) plus methotrexate (MTX) compared with MTX alone and with place...

    Authors: Tanja Alexandra Stamm, Klaus Peter Machold, Daniel Aletaha, Farideh Alasti, Peter Lipsky, David Pisetsky, Robert Landewe, Desiree van der Heijde, Alexandre Sepriano, Martin Aringer, Dimitri Boumpas, Gerd Burmester, Maurizio Cutolo, Wolfgang Ebner, Winfried Graninger, Tom Huizinga…
    Citation: Arthritis Research & Therapy 2018 20:174
  26. Patients with SLE display marked clinical and immunlogical heterogeneity. The purpose of the study was to investigate patterns of serum cytokines in patients with active and stable systemic lupus erythematosus...

    Authors: John A. Reynolds, Eoghan M. McCarthy, Sahena Haque, Pintip Ngamjanyaporn, Jamie C. Sergeant, Elaine Lee, Eileen Lee, Stephen A. Kilfeather, Ben Parker and Ian N. Bruce
    Citation: Arthritis Research & Therapy 2018 20:173
  27. The aim of this study was to measure the association between exposure to commonly used oral osteoarthritis (OA) therapies and relevant confounding risk factors on the occurrence of knee replacement (KR), using...

    Authors: Marc Dorais, Johanne Martel-Pelletier, Jean-Pierre Raynauld, Philippe Delorme and Jean-Pierre Pelletier
    Citation: Arthritis Research & Therapy 2018 20:172
  28. Inflammatory arthritides including rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are associated with increased risk of cardiovascular disease. This process may be driven ...

    Authors: Joshua L. Lee, Premarani Sinnathurai, Rachelle Buchbinder, Catherine Hill, Marissa Lassere and Lyn March
    Citation: Arthritis Research & Therapy 2018 20:171
  29. To examine the activity of the mammalian target of rapamycin (mTOR) pathway and its regulators, transforming growth factor (TGF)-β1 and phosphatase and tensin homolog (PTEN), in minor salivary gland biopsies o...

    Authors: Zeki Soypaçacı, Zeynep Zehra Gümüş, Fulya Çakaloğlu, Mustafa Özmen, Dilek Solmaz, Sercan Gücenmez, Önay Gercik and Servet Akar
    Citation: Arthritis Research & Therapy 2018 20:170
  30. Activation of the NLRP3 inflammasome in gout amplifies the inflammatory response and mediates further damage. In the current study, we assessed the therapeutic effect of OLT1177, an orally active NLRP3 inflamm...

    Authors: Carlo Marchetti, Benjamin Swartzwelter, Marije I. Koenders, Tania Azam, Isak W. Tengesdal, Nick Powers, Dennis M. de Graaf, Charles A. Dinarello and Leo A. B. Joosten
    Citation: Arthritis Research & Therapy 2018 20:169
  31. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease. The dysregulated immune system plays an important role in the pathogenesis of AS. Myeloid-derived suppressor cells (MDSCs) play a key im...

    Authors: Yu-feng Liu, Kun-hai Zhuang, Bin Chen, Pei-wu Li, Xuan Zhou, Hua Jiang, Li-mei Zhong and Feng-bin Liu
    Citation: Arthritis Research & Therapy 2018 20:168
  32. The Assessment of SpondyloArthritis international Society (ASAS) defines a positive family history (PFH) of spondyloarthritis (SpA) as the presence of ankylosing spondylitis (AS), acute anterior uveitis (AAU),...

    Authors: Miranda van Lunteren, Alexandre Sepriano, Robert Landewé, Joachim Sieper, Martin Rudwaleit, Désirée van der Heijde and Floris van Gaalen
    Citation: Arthritis Research & Therapy 2018 20:166
  33. Clinical remission can be maintained after the discontinuation of biological disease-modifying antirheumatic drugs (bDMARDs) in some patients with rheumatoid arthritis (RA) (bDMARD-free remission (BFR)). It is...

    Authors: Motomu Hashimoto, Moritoshi Furu, Wararu Yamamoto, Takanori Fujimura, Ryota Hara, Masaki Katayama, Akira Ohnishi, Kengo Akashi, Shuzo Yoshida, Koji Nagai, Yonsu Son, Hideki Amuro, Toru Hirano, Kosuke Ebina, Ryuji Uozumi, Hiromu Ito…
    Citation: Arthritis Research & Therapy 2018 20:165
  34. Metabolomics is an emerging field of biomedical research that may offer a better understanding of the mechanisms of underlying conditions including inflammatory arthritis. Perturbations caused by inflamed syno...

    Authors: Rekha Narasimhan, Roxana Coras, Sara B. Rosenthal, Shannon R. Sweeney, Alessia Lodi, Stefano Tiziani, David Boyle, Arthur Kavanaugh and Monica Guma
    Citation: Arthritis Research & Therapy 2018 20:164
  35. The aim of this study was to investigate the regulatory role of G-protein coupled receptor 120 (GPR120) in the development and progression of osteoarthritis (OA).

    Authors: Yuanfeng Chen, Dan Zhang, Ki Wai Ho, Sien Lin, Wade Chun-Wai Suen, Huantian Zhang, Zhengang Zha, Gang Li and Po Sing Leung
    Citation: Arthritis Research & Therapy 2018 20:163
  36. Knowledge about predictors of new spinal bone formation in patients with ankylosing spondylitis (AS) is limited. AS-related spinal alterations are more common in men; however, knowledge of whether predictors d...

    Authors: Anna Deminger, Eva Klingberg, Mats Geijer, Jan Göthlin, Martin Hedberg, Eva Rehnberg, Hans Carlsten, Lennart T. Jacobsson and Helena Forsblad-d’Elia
    Citation: Arthritis Research & Therapy 2018 20:162

    The Letter to this article has been published in Arthritis Research & Therapy 2018 20:233

  37. We recently demonstrated that BATF, a member of the activator protein-1 (AP-1) family, regulates osteoarthritic cartilage destruction. Here, we explored the roles and regulatory mechanisms of BATF in collagen-...

    Authors: Sang-Heon Park, Jinseol Rhee, Seul-Ki Kim, Jung-Ah Kang, Ji-Sun Kwak, Young-Ok Son, Wan-Su Choi, Sung-Gyoo Park and Jang-Soo Chun
    Citation: Arthritis Research & Therapy 2018 20:161
  38. Over the last decade, a treat-to-target (T2T) strategy has been recommended for psoriatic arthritis (PsA) and new treatment options have become available. There is a lack of data on PsA regarding any changes t...

    Authors: Glenn Haugeberg, Brigitte Michelsen, Stig Tengesdal, Inger Johanne Widding Hansen, Andreas Diamantopoulos and Arthur Kavanaugh
    Citation: Arthritis Research & Therapy 2018 20:160
  39. To examine the expression of ADAM-17 in rheumatoid arthritis (RA) biological fluids and the role it plays in monocyte adhesion to RA fibroblast-like synoviocytes (FLSs).

    Authors: Sho Ishii, Takeo Isozaki, Hidekazu Furuya, Hiroko Takeuchi, Yumi Tsubokura, Katsunori Inagaki and Tsuyoshi Kasama
    Citation: Arthritis Research & Therapy 2018 20:159
  40. B-cell activating factor of the tumour necrosis factor family (BAFF) plays a role in autoantibody production and is elevated in dermatomyositis (DM) and anti-Jo-1-positive polymyositis (PM). We investigated th...

    Authors: Olga Kryštůfková, Hana Hulejová, Heřman F. Mann, Ondřej Pecha, Ivana Půtová, Louise Ekholm, Ingrid E. Lundberg and Jiří Vencovský
    Citation: Arthritis Research & Therapy 2018 20:158
  41. Systemic sclerosis (SSc) is characterized by vasculopathy and progressive fibrosis. CTLA4-Ig (abatacept) is able to interact with the cell surface costimulatory molecule CD86 and downregulate the target cell. ...

    Authors: Maurizio Cutolo, Stefano Soldano, Paola Montagna, Amelia Chiara Trombetta, Paola Contini, Barbara Ruaro, Alberto Sulli, Stefano Scabini, Emanuela Stratta, Sabrina Paolino, Carmen Pizzorni, Vanessa Smith and Renata Brizzolara
    Citation: Arthritis Research & Therapy 2018 20:157
  42. There is a remarkable lack of detailed knowledge on pain areas in axial spondyloarthritis (axSpA), and their clinical relevance is largely unknown. Pain area may reflect local disease processes, but amplificat...

    Authors: Thijs Willem Swinnen, René Westhovens, Wim Dankaerts and Kurt de Vlam
    Citation: Arthritis Research & Therapy 2018 20:156
  43. This double-blind, active-controlled, randomized, multinational study evaluated the efficacy, safety, pharmacokinetics (PK), and immunogenicity of PF-06438179/GP1111 (IxifiTM/Zessly®), an infliximab biosimilar...

    Authors: Stanley B. Cohen, Rieke Alten, Hideto Kameda, Tomas Hala, Sebastiao C. Radominski, Muhammad I. Rehman, Ramesh Palaparthy, Karl Schumacher, Susanne Schmitt, Steven Y. Hua, Claudia Ianos and K. Lea Sewell
    Citation: Arthritis Research & Therapy 2018 20:155
  44. Pain accompanies rheumatoid arthritis and other chronic inflammatory conditions and is difficult to manage. Although opioids provide potent analgesia, chronic opioid use can cause tolerance and addiction. Rece...

    Authors: Raini Dutta, Mary M. Lunzer, Jennifer L. Auger, Eyup Akgün, Philip S. Portoghese and Bryce A. Binstadt
    Citation: Arthritis Research & Therapy 2018 20:154
  45. Although the effects of interleukin-17A (IL-17A) inhibition on the signs and symptoms of psoriatic arthritis (PsA) are well defined, little is known about its impact of local inflammatory and structural change...

    Authors: Eleni Kampylafka, Isabelle d’Oliveira, Christina Linz, Veronika Lerchen, Fabian Stemmler, David Simon, Matthias Englbrecht, Michael Sticherling, Jürgen Rech, Arnd Kleyer, Georg Schett and Axel J. Hueber
    Citation: Arthritis Research & Therapy 2018 20:153
  46. The molecular heterogeneity of autoimmune and inflammatory diseases has been one of the main obstacles to the development of safe and specific therapeutic options. Here, we evaluated the diagnostic and clinica...

    Authors: João J. Oliveira, Sarah Karrar, Daniel B. Rainbow, Christopher L. Pinder, Pamela Clarke, Arcadio Rubio García, Osama Al-Assar, Keith Burling, Sian Morris, Richard Stratton, Tim J. Vyse, Linda S. Wicker, John A. Todd and Ricardo C. Ferreira
    Citation: Arthritis Research & Therapy 2018 20:152
  47. It is not known if sex-based disparities in immunological factors contribute to the disease process in rheumatoid arthritis (RA). Hence, we examined whether circulating T cell subset proportions and their asso...

    Authors: Jonathan Aldridge, Jayesh M. Pandya, Linda Meurs, Kerstin Andersson, Inger Nordström, Elke Theander, Anna-Carin Lundell and Anna Rudin
    Citation: Arthritis Research & Therapy 2018 20:150
  48. Dysbiosis occurs in spondyloarthritis (SpA) and inflammatory bowel disease (IBD), which is subdivided into Crohn’s disease (CD) and ulcerative colitis (UC). The immunologic consequences of alterations in micro...

    Authors: Emilie H. Regner, Neha Ohri, Andrew Stahly, Mark E. Gerich, Blair P. Fennimore, Diana Ir, Widian K. Jubair, Carsten Görg, Janet Siebert, Charles E. Robertson, Liron Caplan, Daniel N. Frank and Kristine A. Kuhn
    Citation: Arthritis Research & Therapy 2018 20:149
  49. Histone deacetylase inhibitors (HDACi) suppress cytokine production in immune and stromal cells of patients with rheumatoid arthritis (RA). Here, we investigated the effects of the HDACi givinostat (ITF2357) o...

    Authors: Chiara Angiolilli, Pawel A. Kabala, Aleksander M. Grabiec, Marzia Rossato, Wi S. Lai, Gianluca Fossati, Paolo Mascagni, Christian Steinkühler, Perry J. Blackshear, Kris A. Reedquist, Dominique L. Baeten and Timothy R. D. J. Radstake
    Citation: Arthritis Research & Therapy 2018 20:148

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  • Citation Impact 2023
    Journal Impact Factor: 4.4
    5-year Journal Impact Factor: 4.9
    Source Normalized Impact per Paper (SNIP): 1.294
    SCImago Journal Rank (SJR): 1.518

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    Submission to first editorial decision (median days): 9
    Submission to acceptance (median days): 111

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