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6 result(s) for 'Paola Di Benedetto' within Arthritis Research & Therapy

1. Interleukin-32 in systemic sclerosis, a potential new biomarker for pulmonary arterial hypertension

   Pulmonary arterial hypertension (PAH) is a severe complication of systemic sclerosis (SSc), associated with a progressive elevation in pulmonary vascular resistance and subsequent right heart failure and death...

   Authors: Paola Di Benedetto, Giuliana Guggino, Giovanna Manzi, Piero Ruscitti, Onorina Berardicurti, Noemi Panzera, Nicolò Grazia, Roberto Badagliacca, Valeria Riccieri, Carmine Dario Vizza, Ganna Radchenko, Vasiliki Liakouli, Francesco Ciccia, Paola Cipriani and Roberto Giacomelli

   Citation: Arthritis Research & Therapy 2020 22:127

   Content type: Research article Published on: 1 June 2020

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2. Impaired Endothelium-Mesenchymal Stem Cells Cross-talk in Systemic Sclerosis: a Link Between Vascular and Fibrotic Features

   To assess if an impaired cross-talk between endothelial cells (ECs) and perivascular/multipotent mesenchymal stem cells (MSCs) might induce a perturbation of vascular repair and leading to a phenotypic switch ...

   Authors: Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Antonio Francesco Campese, Vasiliki Liakouli, Francesco Carubbi, Ilenia Pantano, Onorina Berardicurt, Isabella Screpanti and Roberto Giacomelli

   Citation: Arthritis Research & Therapy 2014 16:442

   Content type: Research article Published on: 24 September 2014

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3. Blocking Jak/STAT signalling using tofacitinib inhibits angiogenesis in experimental arthritis

   During rheumatoid arthritis (RA), the angiogenic processes, occurring with pannus-formation, may be a therapeutic target. JAK/STAT-pathway may play a role and the aim of this work was to investigate the inhibi...

   Authors: Paola Di Benedetto, Piero Ruscitti, Onorina Berardicurti, Noemi Panzera, Nicolò Grazia, Mauro Di Vito Nolfi, Barbara Di Francesco, Luca Navarini, Antonio Maurizi, Nadia Rucci, Anna Maria Teti, Francesca Zazzeroni, Giuliana Guggino, Francesco Ciccia, Vincenza Dolo, Edoardo Alesse…

   Citation: Arthritis Research & Therapy 2021 23:213

   Content type: Research article Published on: 14 August 2021

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4. Efficacy and safety of rituximab treatment in early primary Sjögren's syndrome: a prospective, multi-center, follow-up study

   Primary Sjögren’s syndrome (pSS) is an autoimmune disorder affecting exocrine glands; however, a subgroup of pSS patients experience systemic extra-glandular involvement leading to a worsening of disease progn...

   Authors: Francesco Carubbi, Paola Cipriani, Alessandra Marrelli, Paola Di Benedetto, Piero Ruscitti, Onorina Berardicurti, Ilenia Pantano, Vasiliki Liakouli, Saverio Alvaro, Alessia Alunno, Antonio Manzo, Francesco Ciccia, Roberto Gerli, Giovanni Triolo and Roberto Giacomelli

   Citation: Arthritis Research & Therapy 2013 15:R172

   Content type: Research article Published on: 30 October 2013

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5. Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: a new potential target for antifibrotic therapy

   Fibrosis may be considered the hallmark of systemic sclerosis (SSc), the end stage triggered by different pathological events. Transforming growth factor-β (TGF-β) and platelet-derived growth factor BB (PDGF-B...

   Authors: Paola Di Benedetto, Vasiliki Liakouli, Piero Ruscitti, Onorina Berardicurti, Francesco Carubbi, Noemi Panzera, Salvatore Di Bartolomeo, Giuliana Guggino, Francesco Ciccia, Giovanni Triolo, Paola Cipriani and Roberto Giacomelli

   Citation: Arthritis Research & Therapy 2018 20:223

   Content type: Research article Published on: 3 October 2018

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6. Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts

   Systemic sclerosis (SSc) is a complex and not fully understood autoimmune disease associated with fibrosis of multiple organs. The main effector cells, the myofibroblasts, are collagen-producing cells derived ...

   Authors: Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Daniela Verzella, Mariafausta Fischietti, Francesca Zazzeroni, Vasiliki Liakouli, Francesco Carubbi, Onorina Berardicurti, Edoardo Alesse and Roberto Giacomelli

   Citation: Arthritis Research & Therapy 2015 17:247

   Content type: Research article Published on: 10 September 2015

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