Figure 8From: Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: a critical reviewChange at week 56 in radiographic end-points in TNF inadequate-response patients treated with rituximab. *P = 0.011, **P = 0.005, ***P < 0.001. Reproduced from Keystone et al. Arthritis Rheum 2008, 59: 785–793 [48], with permission from BMJ Publishing Group Ltd. TNF, tumour necrosis factor.Back to article page