Skip to main content
Figure 2 | Arthritis Research & Therapy

Figure 2

From: Unc93 homolog B1 restricts systemic lethal inflammation by orchestrating TLR7 and TLR9 response

Figure 2

Unc93b1D34A/D34A mice develop systemic lethal inflammation spontaneously. (A) Survival curves of Unc93b1WT/WT, Unc93b1D34A/D34A, or Unc93b1D34A/D34ATlr7-/- mice (blue, red, or green line, respectively). (B and C) Macroscopic images of spleen (B) and liver (C). (D) Microscopic analyses of liver. Histological samples were stained by Hematoxyline and Eosine (H&E) or silver impregnation. (E) Platelet counts in peripheral blood from indicated genotypes of mice. Bars in the graph indicate averages.

Back to article page