Volume 15 Supplement 2

Treatment of SLE: bridging the gap from clinical trials to the clinic

Open Access

Historical overview

  • Leonard H Calabrese1
Arthritis Research & Therapy201315(Suppl 2):A2

DOI: 10.1186/ar4220

Published: 11 July 2013

Medical understanding systemic lupus erythematosus (SLE) has evolved dramatically since its first reference during the 1100s, through the neoclassic period of the 1800s when researchers began to refine the definition, and into the modern era with transformative laboratory investigations and discoveries altering the diagnosis and treatment. Weaved into this historic overview are descriptions of the most important contributions of the leading practitioners and researchers.

Additional file 1 contains an edited transcript of the full presentation.


Authors’ Affiliations

Professor of Medicine, Cleveland Clinic Lerner College of Medicine, RJ Fasenmyer Chair of Clinical Immunology, Cleveland Clinic Foundation


© Calabrese; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.