Ho AM, Johnson MD, Kingsley DM: Role of the mouse ank gene in control of tissue calcification and arthritis. Science. 2000, 289: 265-270. 10.1007/s004030050191.
Article
CAS
Google Scholar
Altman RD, Muniz OE, Pita JC, Howell DS: Articular chondrocalcinosis: Microanalysis of pyrophosphate in synovial fluid and plasma. Arthritis Rheum. 1973, 16: 171-178.
Article
CAS
Google Scholar
Silcox DC, McCarty DJ: Elevated inorganic pyrophosphate concentrations in synovial fluids in osteoarthritis and pseudogout. J Lab Clin Med. 1974, 83: 518-531.
CAS
PubMed
Google Scholar
Ryan LM, Cheung HS, McCarty DJ: Release of pyrophosphate by normal mammalian articular hyaline and fibrocartilage in organ culture. Arthritis Rheum. 1981, 24: 1522-1527.
Article
CAS
Google Scholar
Howell DS, Muniz O, Pita JC, Enis JE: Extrusion of pyrophosphate into extracellular media by osteoarthritic cartilage incubates. J Clin Invest. 1975, 56: 1473-1480.
Article
CAS
Google Scholar
Rosenthal AK, Ryan LM: Ageing increases growth factor-induced inorganic pyrophosphate elaboration by articular cartilage. Mech Ageing Dev. 1994, 75: 35-44. 10.1016/0047-6374(94)90026-4.
Article
CAS
Google Scholar
Ryan LM, Kurup IV, Cheung HS: Transduction mechanisms of porcine chondrocyte inorganic pyrophosphate elaboration. Arthritis Rheum. 1999, 42: 555-560. 10.1002/1529-0131(199904)42:3<555::AID-ANR21>3.0.CO;2-Z.
Article
CAS
Google Scholar
Fedde KN, Blair L, Silverstein J, Coburn SP, Ryan LM, Weinstein RS, Waymire K, MacGregor GR, Narisawa S, Millan JL, Whyte MP: Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia. J Bone Mineral Res. 2000,
Google Scholar
Jung A, Bisaz S, Fleisch H: The binding of pyrophosphate and two diphosphonates by hydroxyapatite crystals. Calc Tiss Res. 1973, 11: 269-280.
Article
CAS
Google Scholar
Okawa A, Nakamura I, Goto S, Moriya H, Nakamura Y, Ikegawa S: Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine. Nature Genetics. 1998, 19: 271-273. 10.1038/956.
Article
CAS
Google Scholar
Terkeltaub R, Rosenbach M, Fong F, Goding J: Causal link between nucleotide pyrophosphohydrolase overactivity and increased intracellular inorganic pyrophosphate generation demonstrated by transfection of cultured fibroblasts and osteoblasts with plasma cell membrane glycoprotein-1: Relevance to calcium pyrophosphate dihydrate crystal deposition disease. Arthritis Rheum. 1994, 37: 934-941.
Article
CAS
Google Scholar
Lotz M, Rosen F, Blanco F, Dudler J, Seegmiller JE, Terkeltaub R: IL-beta suppresses TGFbeta-induced inorganic pyrophosphate (PPi) production and expression of the PPi-generating enzyme PC-1 in human chondrocytes [abstract]. Arthritis Rheum. 1995, 38: S401-
Google Scholar
Terkeltaub R, Goldfine I, Johnson K, Rutsch F, Vaingankar S: Systemic hydroxyapatite crystal deposition disease with periarthritis and arterial calcification: an infantile-onset disease linked to deficiency of the PPi-generating nucleotide pyrophosphohydrolase (NTPPPH) PC-1 [abstract]. Arthritis Rheum. 2000, 43: S281-10.1002/1529-0131(200002)43:2<281::AID-ANR7>3.0.CO;2-7.
Article
Google Scholar
Mahowald M, Krug H, Taurog J: Progressive ankylosis in mice. An animal model of spondyloarthropathy. I. Clinical and radiographic findings. Arthritis Rheum. 1988, 31: 1390-1399.
Article
CAS
Google Scholar
Krug HE, Mahowald ML, Halverson PB, Sallis JD, Cheung HS: Phosphocitrate prevents disease progression in murine progressive ankylosis. Arthritis Rheum. 1993, 36: 1603-1611.
Article
CAS
Google Scholar
Rosenthal AK, Ryan LM: Probenecid inhibits transforming growth factor beta 1 induced pyrophosphate elaboration by chondrocytes. J Rheumatol. 1994, 21: 896-900.
CAS
PubMed
Google Scholar
Rachow JW, Ryan LM, McCarty DJ, Halverson PB: Synovial fluid inorganic pyrophosphate concentration and nucleotide pyrophosphohydrolase activity in basic calcium phosphate deposition arthropathy and Milwaukee shoulder syndrome. Arthritis Rheum. 1988, 31: 408-413.
Article
CAS
Google Scholar
Ryan LM, Wortmann RL, Karas B, McCarty DJ: Cartilage nucleoside triphosphate (NTP) pyrophosphohydrolase. I. Identification as an ecto-enzyme. Arthritis Rheum. 1984, 27: 404-409.
Article
CAS
Google Scholar
Johnson K, Jung A, Murphy A, Andreyev A, Dykens J, Terkeltaub R: Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis Rheum. 2000, 43: 1560-1570. 10.1002/1529-0131(200007)43:7<1560::AID-ANR21>3.3.CO;2-J.
Article
CAS
Google Scholar
Ryan LM, Wortmann RL, Karas B, McCarty DJ: Cartilage nucleoside triphosphate pyrophosphohydrolase. II. Role in extracellular pyrophosphate generation and nucleotide metabolism. Arthritis Rheum. 1985, 28: 413-418.
Article
CAS
Google Scholar
Ryan LM, Kurup IV, Derfus BA, Kushnaryov VM: ATP-induced chondrocalcinosis. Arthritis Rheum. 1992, 35: 1520-1525.
Article
CAS
Google Scholar
Hooijberg JH, Broxterman HJ, Kool M, Assaraf YG, Peters GJ, Noordhuis P, Scheper RJ, Borst P, Pinedo HM, Jansen G: Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. Cancer Res. 1999, 59: 2532-2535.
CAS
PubMed
Google Scholar
Derfus B, Kranendonk S, Camacho N, Mandel N, Kushnaryov V, Ryan L: Human osteoarthritic cartilage matrix vesicles generate both calcium pyrophosphate dihydrate and apatite in vitro. Calcif Tissue Int. 1998, 63: 258-262. 10.1007/s002239900523.
Article
CAS
Google Scholar
Masuda I, Hamada J, Haas AL, Ryan LM, McCarty DJ: A unique ectonucleotide pyrophosphohydrolase associated with porcine chondrocyte-derived vesicles. J Clin Invest. 1995, 95: 699-704.
Article
CAS
Google Scholar
Cheung HS, Kurup IV, Sallis JD, Ryan LM: Inhibition of calcium pyrophosphate dihydrate crystal formation in articular cartilage vesicles and cartilage by phosphocitrate. J Biol Chem. 1996, 271: 28082-28085. 10.1074/jbc.271.45.28082.
Article
CAS
Google Scholar
Gibilisco PA, Schumacher HR, Hollander JL, Soper KA: Synovial fluid crystals in osteoarthritis. Arthritis Rheum. 1985, 28: 511-515.
Article
CAS
Google Scholar
Ryan LM, Cheung HS: The role of crystals in osteoarthritis. Rheum Dis Clin North Am. 1999, 25: 257-267.
Article
CAS
Google Scholar