Buckwalter JA, Mankin HJ, Grodzinsky AJ: Articular cartilage and osteoarthritis. Instructional Course Lectures. 2005, 54: 465-480.
PubMed
Google Scholar
Bramono DS, Richmond JC, Weitzel PP, Kaplan DL, Altman GH: Matrix metalloproteinases and their clinical applications in orthopaedics. Clin Orthop Relat Res. 2004, 428: 272-285. 10.1097/01.blo.0000144166.66737.3a.
Article
PubMed
Google Scholar
Ushiyama T, Inoue K, Nishioka J: Expression of estrogen receptor related protein (p29) and estradiol binding in human arthritic synovium. J Rheumatol. 1995, 22: 421-426.
CAS
PubMed
Google Scholar
Khalkhali-Ellis Z, Seftor EA, Nieva DR, Handa RJ, Price RH, Kirschmann DA, Baragi VM, Sharma RV, Bhalla RC, Moore TL, Hendrix MJ: Estrogen and progesterone regulation of human fibroblast-like synoviocytes function in vitro: implications in rheumatoid arthritis. J Rheumatol. 2000, 27: 1622-1631.
CAS
PubMed
Google Scholar
Kapila S, Xie YQ: Targeted induction of collagenase and stromelysin by relaxin in unprimed and β-estradiol-primed diarthrodial joint fibrocartilaginous cells but not in synoviocytes. Lab Invest. 1998, 78: 925-938.
CAS
PubMed
Google Scholar
Warren MP, Fried JL: Temporomandibular disorders and hormones in women. Cells Tissues Organs. 2001, 169: 187-192. 10.1159/000047881.
Article
CAS
PubMed
Google Scholar
Carlsson GE, LeResche L: Epidemiology of temporomandibular disorders. Progress in Pain Research and Management: Temporomandibular Disorders and Related Pain Conditions. Edited by: Sessle BJ, Bryant PS, Dionne RA. 1995, Seattle: IASP Press, 211-226.
Google Scholar
Sheffield LG, Anderson RR: Effect of estradiol and relaxin on collagen and non-collagen protein synthesis by mammary fibroblasts. Life Sci. 1984, 35: 2199-2203. 10.1016/0024-3205(84)90460-0.
Article
CAS
PubMed
Google Scholar
Too CK, Kong JK, Greenwood FC, Bryant-Greenwood GD: The effect of oestrogen and relaxin on uterine and cervical enzymes: Collagenase, proteoglycanase and beta-glycuronidase. Acta Endocrinology (Copenh). 1986, 111: 394-403.
CAS
Google Scholar
Mushayandebvu TI, Rajabi MR: Relaxin stimulates interstitial collagenase activity in cultured uterine cervical cells from nonpregnant and pregnant but not immature guinea pigs; estradiol-17 beta restores relaxin's effect in immature cervical cells. Biol Reprod. 1995, 53: 1030-1037. 10.1095/biolreprod53.5.1030.
Article
CAS
PubMed
Google Scholar
Hwang JJ, Lin SW, Teng CH, Ke FC, Lee MT: Relaxin modulates the ovulatory process and increases secretion of different gelatinases from granulosa and theca-interstitial cells in rats. Biol Reprod. 1996, 55: 1276-1283. 10.1095/biolreprod55.6.1276.
Article
CAS
PubMed
Google Scholar
Samuel CS, Butkus A, Coghlan JP, Bateman JF: The effect of relaxin on collagen metabolism in the nonpregnant rat pubic symphysis: the influence of estrogen and progesterone in regulating relaxin activity. Endocrinology. 1996, 137: 3884-3890. 10.1210/en.137.9.3884.
CAS
PubMed
Google Scholar
Samuel CS, Coghlan JP, Bateman JF: Effects of relaxin, pregnancy and parturition on collagen metabolism in the rat pubic symphysis. J Endocrinol. 1998, 159: 117-125. 10.1677/joe.0.1590117.
Article
CAS
PubMed
Google Scholar
Goldsmith LT, Crob HS, Scherer KJ, Surve A, Steinetz BG, Weiss G: Placental control of ovarian immunoreactive relaxin secretion in the pregnant rat. Endocrinology. 1981, 109: 584-592.
Article
Google Scholar
Sherwood OD: Relaxin. The Physiology of Reproduction. Edited by: Knobil E, Neill J. 1994, New York: Raven Press, 861-1009.
Google Scholar
O'Day-Bowman MB, Winn RJ, Dzuik PJ, Lindley ER, Sherwood OD: Hormonal control of the cervix in pregnant gilts. III. Relaxin's influence on cervical biochemical properties in ovariectomized hormone-treated gilts. Endocrinology. 1991, 129: 1967-1976.
Article
PubMed
Google Scholar
Sherwood OD, Downing SJ, Guico LM: The physiological effects of relaxin during pregnancy: studies in rats and pigs. Oxf Rev Reprod Biol. 1993, 15: 143-149.
CAS
PubMed
Google Scholar
Cheah SH, Sherwood OD: Effect of preparturient 17 beta-estradiol and relaxin on parturition and pup survival in the rat. Endocrinology. 1988, 122: 1958-1963.
Article
CAS
PubMed
Google Scholar
Palejwala S, Stein DE, Weiss G, Monia BP, Tortoriello D, Goldsmith LT: Relaxin positively regulates matrix metalloproteinase expression in human lower uterine segment fibroblasts using a tyrosine kinase signaling pathway. Endocrinology. 2001, 142: 3405-3413. 10.1210/en.142.8.3405.
Article
CAS
PubMed
Google Scholar
Lenhart JA, Ryan PL, Ohleth KM, Palmer SS, Bagnell CA: Relaxin increases secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 during uterine and cervical growth and remodeling in the pig. Endocrinology. 2001, 142: 3941-3949. 10.1210/en.142.9.3941.
Article
CAS
PubMed
Google Scholar
Naqvi T, Duong T, Hashem G, Shiga M, Zhang Q, Kapila S: Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants. Arthritis Res Ther. 2004, 7: R1-R11.
Article
PubMed Central
PubMed
Google Scholar
Hall JA, Anthony RV: Influence of ovarian steroids on relaxin-induced distensibility and compositional changes in the porcine cervix. Biol Reprod. 1993, 48: 1348-1353. 10.1095/biolreprod48.6.1348.
Article
CAS
PubMed
Google Scholar
Chen B, Wen Y, Yu X, Polan ML: Elastin metabolism in pelvic tissues: is it modulated by reproductive hormones?. Am J Obstet Gynecol. 2005, 192: 1605-1613. 10.1016/j.ajog.2004.11.027.
Article
CAS
PubMed
Google Scholar
Abubaker AO, Hebda PC, Gunsolley JN: Effects of sex hormones on protein and collagen content of the temporomandibular joint disc of the rat. J Oral Maxillofac Surg. 1996, 54: 721-727. 10.1016/S0278-2391(96)90690-4.
Article
CAS
PubMed
Google Scholar
Yasuoka T, Nakasbima M, Okuda T, Tatematsu N: Effect of estrogen replacement on tempromandibular joint remodeling in ovariectomized rats. J Oral Maxillofac Surg. 2000, 58: 189-196. 10.1016/S0278-2391(00)90337-9.
Article
CAS
PubMed
Google Scholar
Unemori EN, Beck LS, Lee WP, Xu Y, Siegel M, Keller G, Liggitt HD, Bauer EA, Amento EP: Human relaxin decreases collagen accumulation in vivo in two rodent models of fibrosis. J Invest Dermatol. 1993, 101: 280-285. 10.1111/1523-1747.ep12365206.
Article
CAS
PubMed
Google Scholar
Kapila S: Does the relaxin, estrogen and matrix metalloproteinase axis contribute to degradation of TMJ fibrocartilage?. J Musculoskelet Neuronal Interact. 2003, 3: 401-405.
CAS
PubMed
Google Scholar
Knudson CB, Knudson W: Hyaluronan and CD44: modulators of chondrocyte metabolism [Review]. Clin Orthop Relat Res. 2004, S152-162. 10.1097/01.blo.0000143804.26638.82.
Google Scholar
Kalya S, Rosenthal AK: Extracellular matrix changes regulate calcium crystal formation in articular cartilage. Curr Opin Rheumatol. 2005, 17: 325-329. 10.1097/01.bor.0000160783.14798.10.
Article
CAS
PubMed
Google Scholar
Hecht JT, Hayes E, Haynes R, Cole WG: COMP mutations, chondrocyte function and cartilage matrix. Matrix Biol. 2005, 23: 525-533. 10.1016/j.matbio.2004.09.006.
Article
CAS
PubMed
Google Scholar
Haskin CL, Milam SB, Cameron IL: Pathogenesis of degenerative joint disease in the human temporomandibular joint. Crit Rev Oral Biol Med. 1995, 6: 248-277.
Article
CAS
PubMed
Google Scholar
Wang W, Hayami T, Chen C, Kapila S: Relaxin and estrogen receptor expression in TMJ and meniscus fibrocartilages [abstract]. J Den Res. 2006, 85 (spec iss A): 0021-
Google Scholar
Unemori EN, Pickford LB, Salles AL, Piercy CE, Grove BH, Erikson ME, Amento EP: Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo. J Clin Invest. 1996, 98: 2739-2745.
Article
PubMed Central
CAS
PubMed
Google Scholar
Unemori EN, Amento EP: Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts. J Biol Chem. 1990, 265: 10681-10685.
CAS
PubMed
Google Scholar
Eddie LW, Bell RJ, Lester A, Geier M, Bennet G, Johnston PD, Niall HD: Radioimmunoassay of relaxin in pregnancy with an analogue of human relaxin. Lancet. 1986, 1: 1344-1346. 10.1016/S0140-6736(86)91662-4.
Article
CAS
PubMed
Google Scholar
Bell RJ, Eddie LW, Lester AR, Wood EC, Johnston PD, Niall HD: Relaxin in human pregnancy serum measured with a homologous RIA. Obstet Gynecol. 1987, 69: 585-589.
CAS
PubMed
Google Scholar
Stewart DR, Celniker AC, Taylor CA, Cragun JR, Overstreet J, Lasley B: Relaxin in the peri-implantation period. J Clin Endocrinol Metab. 1990, 70: 1771-1773.
Article
CAS
PubMed
Google Scholar