Mesenchymal stromal cells: Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation

Table 1 Surface antigens commonly identified during isolation of mesenchymal stem cells (MSCs)

		Number of populations reported with specified antigen levels^b
		Human MSCs^c			Murine MSCs^c
Marker type	Surface antigen^a	+	+/-	-	+	+/-	-	References
Positive	Stro-1	7	1	2	0	0	0	4–7,66,82–84
	CD13	5	0	0	1	0	1	2,12,84–87,89–90
	CD29	5	0	0	11	0	0	2,12,63,84–87,90
	CD44	11	0	1	10	1	0	2,63,82,84–87,90–91
	CD73	5	0	0	0	0	0	2,10,83–85
	CD105	7	0	0	1	0	0	2,10,12,83–87
	CD106	4	0	2	4	1	0	2,5,83–84,86–89
Negative	CD11b	0	0	3	0	1	5	2,82,86–88,90
	CD31	0	3	10	0	0	6	2,82,84–91
	CD34	1	1	10	5	6	3	2,12,63,82,84–89,91
	CD45	0	0	11	0	0	6	2,82,84–91
	CD117	0	2	3	1	1	13	2,63,82,87–90
Variable	Sca-1	0	0	0	6	5	4	63,87–88,90
	CD10	6	0	5	0	1	0	82,85–87,89
	CD90	11	1	1	2	4	10	2,12,63,82,84–85,87–91
	Flk-1	2	1	1	0	0	5	82,88–89

^aAntigen chosen if tested in at least 4 MSC populations from the 19 papers reviewed; ^bnumber of MSC populations (isolated from various tissues from human or mouse) reported in these studies to be mostly positive (+), somewhat positive (+/-), or negative (-); ^cMSCs isolated primarily from bone marrow but also from fat, skin, thymus, kidney, muscle, liver, lung, and placenta.

ISSN: 1478-6362