|
Linkage region
|
LOD
|
Cohort ethnicity
|
Stratification criteria
|
Ref(s)
|
|---|
|
2q34*
|
P = 0.00002†
|
AA
|
Nephritis
|
[93,94]
|
|
5p15
|
6.2
|
EA, AA, HIS
|
Alleged rheumatoid arthritis
|
[98,99]
|
|
5q14
|
5.0
|
EA
|
Autoimmune thyroid disease
|
[100]
|
|
11p13
|
3.7
|
AA
|
Discoid lupus, thrombocytopenia
|
[101,102]
|
|
11q14
|
4.7
|
AA
|
Hemolytic anemia, nucleolar ANA
|
[102-104]
|
|
17p12
|
4.0
|
EA
|
Vitiligo
|
[22,105]
|
|
19p13.2
|
3.6
|
EA
|
Anti-dsDNA
|
[87,106]
|
- *This region is orthologous to that containing the mouse lupus susceptibility locus sle7 [107]. †The 2q34 region was analyzed using sib-pair methods; therefore, a P value is generated instead of a log of odds (LOD) score. AA, African-American; ANA, anti-nuclear antibody; EA, European-American; HIS, Hispanic; OMRF, Oklahoma Medical Research Foundation.
