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Table 3 Genes associated with systemic lupus erythematosus

From: Current status of lupus genetics

Gene name Locus ID Location Evidence
C1Q 712 1p36 Causative mutations found [27,35]
C2 717 6p21 Causative mutations found [28,29]
C4 721 6p21 Causative mutations found [33,35]
PTPN22 26,191 1p13 Meta-analysis [47]
FCGR2A 2,212 1q23 Meta-analysis [9,12]
FCGR3A 2,214 1q23 Meta-analysis [10,12]
IL10 3,586 1q32 Meta-analysis [43]
CTLA4 1,493 2q33 Meta-analysis [45]
HLA-DRB1 3,123 6p21 Multiple positive reports [4,26,37]
TNFα 7,124 6p21 Meta-analysis [46]
TNFβ 4,049 6p21 Multiple positive reports [26]
MBL 4,153 10q11 Meta-analysis [44]