Table 1 The five main groups of matrix metalloproteinases
From: Proteinases in the joint: clinical relevance of proteinases in joint destruction
Group | MMPs |
|---|---|
Collagenases | MMP-1 (collagenase-1), MMP-8 (collagenase-2), |
| Â | MMP-13 (collagenase-3), |
| Â | MMP-18 (collagenase-4) |
Gelatinases | MMP-2 (gelatinases A), MMP-9 (gelatinases B) |
Stromelysins | MMP-3 (stromelysin-1), MMP-10 (stromelysin-2), |
| Â | MMP-11 (stromelysin-3) |
Matrilysins | MMP-7, MMP-26 |
MT MMPs | MMP-14 (MT1-MMP), MMP-15 (MT2-MMP), |
| Â | MMP-16 (MT3-MMP), MMP-17 (MT4-MMP), |
| Â | MMP-24 (MT5-MMP), MMP-25 (MT6-MMP) |