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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study

Figure 3

Signalling pathways of proteinase-activated receptor 2 (PAR-2) synthesis. PAR-2 immunostaining in osteoarthritic cartilage untreated (n = 4) and treated with SB 202190 (inhibitor of p38; n = 3), PD 98059 (inhibitor of MEK1/2; n = 4), and SN50 (inhibitor of nuclear factor-kappa B; n = 4). P value indicates the comparison with the untreated (CTL) specimens. MEK1/2, mitogen-activated protein kinase kinase.

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Arthritis Research & Therapy

ISSN: 1478-6362

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